Investigate into conolidine has led to discovery of an opioid receptor in the body identified as ACKR3/CXCR7. ACKR3 appears to be by far the most desired target for conolidine, which also disregards the other 4 classical opioid receptors(3). Presented the mechanism of action of conolidine in contrast to opioids https://bookmarkfavors.com/story6484911/alternative-natural-pain-relief-to-replace-traditional-painkillers-for-dummies