Epidural clonidine used as an adjunct to regional anesthetics has three different mechanisms of action. To start with, the stimulation of alpha-two-receptors within the dorsal horn decreases agony transmission. Secondly, clonidine could potentially cause regional vasoconstriction that limitations vascular elimination of local epidural anesthetics. Critical Allergic Reactions. Clonidin... https://jasoni385ctl0.wikiconversation.com/user