In fact, TERT phosphorylation is shown being essential for telomerase activation. b Impact of BETi on telomere regulation. BETi contend with acetylated histones for your binding in the BRD4 bromodomains releasing BRD4 from shorter telomere, destabilizing telomere defense intricate organization and cutting down Telomerase activity. The progressive shortening of telomere https://jq-1-role-in-gene-regula91345.blogsmine.com/32346087/not-known-factual-statements-about-jq-1-inhibition-of-brd4